Parkinson's disease (PD)
is a progressive neurodegenerative disorder associated with a loss of dopaminergic nigrostriatal neurons.
Dopamine is a chemical used in body movement.
A person with Parkinson's has abnormally low dopamine levels.
Deficiency of dopamine generally occurs in patients over 50 years.
Signs and symptoms:
- Tremor: Tremor is present and most prominent with the limb at rest. The tremor may appear as a pill-rolling motion of the hand or a simple oscillation of the hand or arm.
- Bradykinesia : Bradykinesia refers to slowness of voluntary movement. Bradykinesia is also expressed as micrographia (small handwriting), hypomimia (decreased facial expression),decreased blink rate and hypophonia (soft speech)
- Postural instability